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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCN2A
All Species:
31.21
Human Site:
S589
Identified Species:
68.67
UniProt:
Q99250
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99250
NP_001035232.1
2005
227975
S589
G
R
A
K
D
I
G
S
E
N
D
F
A
D
D
Chimpanzee
Pan troglodytes
XP_001153227
2005
227953
S589
G
R
A
K
D
I
G
S
E
N
D
F
A
D
D
Rhesus Macaque
Macaca mulatta
XP_001099608
2005
228017
S589
G
R
T
K
D
I
G
S
E
N
D
F
A
D
D
Dog
Lupus familis
XP_858129
2006
227947
S589
G
R
T
K
D
I
G
S
E
N
D
F
A
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q62205
1984
225794
S565
G
R
G
R
D
L
G
S
E
T
E
F
A
D
D
Rat
Rattus norvegicus
P04775
2005
227855
S589
G
R
V
K
D
I
G
S
E
N
D
F
A
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512686
2008
228349
S591
G
R
A
K
D
V
G
S
E
N
D
F
A
D
D
Chicken
Gallus gallus
XP_422025
2006
228269
S589
G
R
A
K
D
V
G
S
E
N
D
F
A
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
Q545
M
E
G
L
E
D
A
Q
R
P
C
P
P
G
W
Tiger Blowfish
Takifugu rubipres
Q2XVR7
1892
213080
T557
T
A
A
A
S
V
A
T
A
A
A
S
V
A
T
Fruit Fly
Dros. melanogaster
P35500
2131
239344
L607
Y
Q
D
A
Q
Q
H
L
P
Y
A
D
D
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
98.6
N.A.
77.8
97.7
N.A.
95
92.2
N.A.
63.2
61.6
45.3
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.9
99.4
N.A.
86.8
98.9
N.A.
98
96.6
N.A.
74.9
74.5
62.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
66.6
93.3
N.A.
93.3
93.3
N.A.
0
6.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
100
100
N.A.
6.6
20
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
46
19
0
0
19
0
10
10
19
0
73
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
73
10
0
0
0
0
64
10
10
73
73
% D
% Glu:
0
10
0
0
10
0
0
0
73
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% F
% Gly:
73
0
19
0
0
0
73
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
64
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
10
10
0
0
% P
% Gln:
0
10
0
0
10
10
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
73
0
10
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
73
0
0
0
10
0
10
0
% S
% Thr:
10
0
19
0
0
0
0
10
0
10
0
0
0
0
10
% T
% Val:
0
0
10
0
0
28
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _